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Pain Relief: LDN is known to reduce pain by blocking the reception of pain signals and increasing endorphins, which naturally alleviate pain

These characteristics are consistent with its identity as a small linear peptide rather than a cyclized or cross-linked peptide structure

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No comprehensive, long-term human safety studies have been published

J Exp Bot 66: 19351950 Mhamdi A, Hager J, Chaouch S, Queval G, Han Y, Taconnat L, Saindrenan P, Gouia H, Issakidis-Bourguet E, Renou JP, et al