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Lifestyle factors significantly influence healing speed and quality, amplifying or undermining the peptides effects

Antioxidant mechanisms include enhanced expression of molecules that can modulate ROS accumulation by both enzymatic and nonenzymatic meansGlutathione (GSH) is an antioxidant that acts as a free radical scavenger and a detoxifying agent in cells

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Male rats with PTSD-like behaviors showed elevated p -cresol (a neurotoxic metabolite linked to overgrowth of Ruminococcaceae and Lachnospiraceae ) in prefrontal cortex, leading to dopaminergic dysfunction with increased DA, increased dopamine metabolite 3,4-dihydroxyphenylacetic acid (DOPAC), and significantly elevated DA D3 receptor expression compared to controls (Laudani et al., 2023)

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