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The processes behind the release of insulin and GLP-1 are significantly influenced by Gq signaling 29,33
Both alcohol and [GLP-1 drugs] can decrease blood sugar levels, and this could be dangerous, particularly in those that are also on insulin or other blood-sugar-lowering medications, says Brianna Johnson-Rabbett, MD, the interim medical director of the American Board of Obesity Medicine
New England Journal of Medicine, 393 (18), 17961806
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doi:10.1016/0003-2697(88)90564-7