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Thompson, J

We found that the SAM/SAH ratio, known as the methylation index because it indicates the methylation capacity of an organism 36 , was significantly increased during in vivo reprogramming (Extended Data Fig

In Summary: The oxidative phase of the pentose phosphate shunt can generate NADPH, without generating a net increase of ribose-phosphate by using the ribose-phosphate sugars formed as substrates for the non-oxidative phase, which converts them to fructose-6-phosphate and glyceraldehyde-3-phosphate that can then enter the glycolytic pathway

This is not an exhaustive list of the therapeutic effects observed in BPC-157

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(2013) published in Molecular and Cellular Biochemistry