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If the price is high relative to the benefit, NICE can restrict access to specific patient groups (for example, only those with very high BMI or particular comorbidities), or reject NHS use altogether

Our clinicians will assess your information to determine whether your chosen treatment is suitable for your circumstances before your order is passed to our General Pharmaceutical Council-registered pharmacy for dispatch

Freezing causes ice crystal formation that physically disrupts the peptides tertiary structure, resulting in 4060% potency loss after a single freeze-thaw cycle

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When tesamorelin is the more appropriate choice Tesamorelin is typically the preferred agent when: Visceral adipose tissue is the primary treatment target, particularly with associated metabolic comorbidities A clinician is working within a framework that prioritises FDA-approved agents The patient has HIV-associated lipodystrophy, the only approved indication A robust evidence base is required for clinical decision-making For general somatopause-related concerns gradual changes in body composition, sleep quality, and recovery the CJC-1295/ipamorelin combination remains more commonly used, primarily because of its flexible dosing profile and the preserved pulsatile GH release pattern