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It has not received MHRA approval, there is no UK SmPC, and it is not available through NHS prescribing pathways

This stepwise approach is designed to assess gastrointestinal tolerance and evaluate dose-dependent metabolic endpoints

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According to FDA prescribing information, injection site reactions vary by dose and formulation, with clinical trials showing rates of approximately 1.7-5.2% for Mounjaro and 2.4-5.3% for Zepbound, depending on the dose used

Therefore, we performed pharmacokinetic studies of BPC157 in beagle dogs following single IV administration at a dose of 6 g/kg, single IM administration at doses of 6, 30, or 150 g/kg, and repeated IM administration at a dose of 30 g/kg for seven consecutive days