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In light of these intracellular observations (Kokame et al, 1996), we hypothesize that changes in the intracellular redox state associated with elevated homocysteine levels can alter the expression of multiple genes involved in other specific cellular functions that could be partially responsible for vascular disorders associated with moderate hyperhomocysteinemia
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Lamb CA, Kennedy NA, Raine T, Hendy PA, Smith PJ, Limdi JK, et al
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