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Yes, some people do experience fatigue

On a 1.0mL syringe, each line represents a larger volume increment, reducing precision but allowing draws up to 100 units

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To translate visual co-localization observed in traditional microscopy into quantifiable physical proximity, the last decade has seen the rapid evolution of genetically encoded contact sensors

This article covers the biological mechanisms at play, the timing and dosage considerations that matter, and the honest limitations of the current evidence base