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These cells are responsible for a variety of critical tasks, including the contraction and relaxation of the blood vessels

"Deficient synthesis of glutathione underlies oxidative stress in aging." Am J Clin Nutr

2018;118:709-718.[DOI] 114

C th l superoxide, nitric oxide, cc gc carbon, hydroperoxit, peroxynitrit, lipid peroxit,

In contrast, Nrf2 activators, such as sulforaphane, have been found to prevent homocysteine- or hydrogen peroxide-induced cataract formation in human lens epithelial cells by increasing nuclear translocation of Nrf2 and expressions of cellular antioxidants, including catalase, superoxide dismutase, glutathione peroxidase, and glutathione

This knowledge now opens novel ways to improve interventions that could combat age-related muscle atrophy and impaired regeneration with fibrosis and fat infiltration (including sarcopenia and frailty)