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Chemically targeting the redox switch in AP1 transcription factor FOSB

For derivatization, 10 L of methoxyamine hydrochloride in pyridine (20 mg/mL) was added to each sample and then shaken at 30 C for 90 min, followed by the addition of 91 L of a fatty acid methyl ester (FAMEs) and N-methyl-N-(trimethylsilyl) trifluoroacetamide (MSTFA) mixture, which was shaken for 30 min at 37 C

In accord with past work, Pol -dependent products with longer complementary sequence additions were comparatively rare ( + TC, +CTC) (Supplementary Fig

Concentrations below 12 mg/mL push the dose volume over 1 mL, requiring two syringes or a tuberculin syringe