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the lysine residue preceding the active site, which forms electrostatic interactions with the carboxyl group of the glycine in GSH, the active site cysteines and polar amino acids interacting with the carboxyl group of the glutamate in GSH are conserved in most ROXYs, suggesting that GSH binding might be required for activity

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10.1002/jbt.22942 45 LuB.LiJ.GuiM.YaoL.FanM.ZhouX.et al (2022)