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GLP-1RGIPR co-agonism is effective in the management of obesity and type 2 diabetes 1,2 , and lanifibranora nuclear-acting small-molecule triple agonist of PPAR, PPAR and PPARis in clinical phase 3 trials for the treatment of metabolic dysfunction-associated steatohepatitis 3
Saxenda (Liraglutide) Saxenda is a once-daily injectable weight loss drug that mimics the GLP-1 hormone, helping reduce hunger and calorie intake
Clinical trials suggest its generally well-tolerated, but a few key points stand out
Most of this is water and glycogen, not fat
However, high doses may increase irritability or restlessness
CIF=cumulative incidence function
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