A B6 deficiency can lead to a 30-40% decrease in serotonin levels
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SOPs that arent followed are in some ways worse than no SOPs at all
For myocardial hypertrophy, potential decisions include who needs closer follow-up, who is likely to progress to HFpEF, who may regress after pressure unloading, who has metabolically reversible remodeling, who should receive a metabolic intervention, and who is at risk of treatment toxicity
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If GI side effects are severe at any step, hold the current dose for an extra 4 weeks before escalating