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Fernandes, R

Uno H, Kurata S

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In a mouse model with CD68-driven macrophage depletion, reduced macrophages lead to an imbalance in M1/M2 polarization, with a predominance of M2 type, inducing spontaneous PAH accompanied by PASMCs proliferation (Zawia et al., 2021)

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Caspase-1 engages full-length Gasdermin D through two distinct interfaces that mediate caspase recruitment and substrate cleavage