4.1.1 GLP1-RAs attenuate the inflammation in MASLD by downregulating multiple inflammatory factors In animal models, GLP-1RAs have shown promising results in decreasing the expression of various inflammatory markers, including TLR2 and C-X3-C chemokine receptor 1 (CX3CR1), as well as reducing the expression of genes related to liver fibrosis and fat accumulation
The Phase 2 and Phase 3 trials so far have shown a safety profile broadly consistent with other GLP-1 medications: gastrointestinal side effects are common, and a new signal called dysaesthesia (an abnormal skin sensation) appears more often at higher doses
Mortazavi, S
Green Tea / EGCG Green tea extract high in Epigallocatechin gallate (EGCG) is another popular GLP-1 supplement
Although not as commonly encountered as other Boiga species, Boiga melanota shares many of the same traits that define the genus, including arboreal movement, nocturnal activity, and a reactive feeding response
Headaches Headaches are another less common side effect