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In the SUSTAIN clinical trial program, the average HbA1c reductions ranged from 1.45% to 1.55%, depending on the dose (0.5 mg to 1 mg weekly)
It would also assist in further weight loss or reduction in other medications to reduce polypharmacy. Oral semaglutide is only currently approved for treating type 2 diabetes, with only two GLP-1-related injectables liraglutide and Wegovy approved for treating obesity
It is given in cases where oral administration is not possible
10.1016/j.freeradbiomed.2018.05.075 Free Radical
Investigation of nerve fibers in the skin by biopsy: technical aspects, indications, and contribution to diagnosis of small-fiber neuropathy
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