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reconstituted solutions stable for ~28 days MOTS-c Research Profile MOTS-c is a 16-amino acid peptide encoded in mitochondrial DNA, relatively new to the peptide research space but accumulating a compelling body of available data: Improves insulin sensitivity and glucose tolerance in multiple models Activates AMPK the same pathway activated by metformin and physical exercise Research in aged subjects showed restoration of youthful metabolic function Short half-life requires frequent dosing (daily to every-other-day) for consistent serum levels Generally well-tolerated with minimal reported adverse events in research literature Requires cold chain storage
Position of the Academy of Nutrition and Dietetics: Nutrition and Athletic Performance
In addition to controlling blood sugar and supporting weight loss, GLP-1 drugs, and SGLT-2 inhibitors offer other significant benefits
R.TsapasA.et al (2022)
These combined effects can help with both blood sugar management and gradual weight loss
doi: 10.1016/S2468-1253(20)30217-X 2
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