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WES remains vastly underutilized in non-oncological adult medicine, including in liver disease
The sample preparation protocol is based on the simultaneous reduction with TCEP of disulfide bonds and derivatization of thiol groups with BCPB and the deproteinization of the mixture with PCA
The animals were then perfused with cold saline to free them of residual blood, after which liver and other tissues were collected immediately, weighed, quickly diced, and frozen in liquid nitrogen at 80 C
The safety of liraglutide (and exenatide) can only truly be assessed with robust phase IV postmarketing data involving long-term treatment with this novel therapy
Astroglial NMDA receptors inhibit expression of K4.1 channels in glutamate-overexposed astrocytes in vitro and in the brain of rats with acute liver failure
Zilu et al
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