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The weight loss is clinically important, as most individuals with type 2 diabetes are overweight or obese, but also because there is an unmet need for safe, effective, and durable weight loss interventions in obese individuals without diabetes

Month 5 After 5 months, a reduction in HbA1c level was 1.3 % and the fasting glucose levels were 6.3 mmol/L compared to the baseline (9.6 mmol/L)

What are the side effects, and can they be mitigated

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Tirzepatide affects appetite, blood sugar regulation, and digestion, which can help address metabolic changes that occur during perimenopause and menopause

Some effects appear to be direct, while others are likely secondary to weight loss and improved insulin sensitivity