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Financial Impacts at Federal and State Levels Federal Level Increased Spending: Medicare spending on GLP-1 medications could rise by $24$37 billion over the next several years, depending on the breadth of the coverage expansion and member uptake rates

Statistical significance was assessed using two-tailed unpaired t-tests with false discovery rate (FDR) correction using the two-stage step-up method of Benjamini, Krieger and Yekutieli (Q = 1%)

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Patients should inform their healthcare provider of all medications and supplements they are taking to minimize the risk of adverse interactions, and healthcare professionals should evaluate each regimen prior to initiating glutathione therapy