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LEADER Steering Committee on behalf of the LEADER Trial Investigators
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In summary, these data provide evidence that long-term IGF-1R blockade with mAbs is feasible, well tolerated, and can recapitulate effects observed with genetic disruption of IGF-1R signaling on lifespan
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Larazotide , also known as Larazotide acetate (LA), is a synthetic peptide that is made up of a single-chain peptide of eight amino acids that acts as a tight junction regulator to restore intestinal barrier function (Slifer et al., 2021)
And this is a pilot too
