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Since Sikiric et al 47 firstly demonstrated that NO generation in gastric mucosa contributes to the anti-ulcer effect of BPC 157 in gastric lesion, subsequently, several reports analyzed the role of NO modulation in the healing effect of BPC 157 in different tissue injuries by using NO-synthase-blockade L-NAME or NO-system overstimulation L-arginine
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This scoring system allowed for semi-quantitative evaluation of cartilage integrity based on macroscopic features such as softening, fibrillation, erosion, ulceration, and complete cartilage loss [1]
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