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Although direct in vivo evidence for lichen mediated modulation of these pathways remains limited, similar regulatory effects on HIF-1 and TGF- signaling have been described for various natural secondary metabolites in non-lichen systems, providing mechanistic context
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10.1016/j.molcel.2013.02.008 106 Willems L., Jacque N., Jacquel A., Neveux N., Trovati Maciel T., Lambert M., Schmitt A., Poulain L., Green A
Research shows increases in adiponectin, a hormone produced by fat cells that improves insulin sensitivity and has anti-inflammatory properties
R., Xu, Y., and Cyster, J
