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In addition, a head-to-head trial of semaglutide and liraglutide was conducted in the STEP 8 trial, with a mean weight loss of 17.1% in the semaglutide group, which was significantly more effective than liraglutide (mean weight loss of 6.6%)

These advancements offer hope for a more comprehensive and personalised approach to weight loss, potentially reducing the burden of obesity and its associated health problems.

Needles become blunt after a single use, making subsequent injections more painful and increasing the risk of skin trauma and infection

If worsening: Add topical lidocaine for the most affected areas

There is no clinical trial data here, but the clinical concern is real and growing

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