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Binding to HSA causes an increase in hydrodynamic volume, which slows renal clearance 13,14
Bioavailability and dosing basics Oral absorption of carnitine is limited and regulated by intestinal transporters and the kidneys
doi: 10.1016/j.tem.2012.11.008 11 TsengCCJarboeLAWolfeMM
These alterations not only extend its duration of action but also enable IGF-1 LR3 to circumvent binding with IGF-binding proteins, which typically impede the biological availability and efficacy of IGF-1
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