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Associated with sleep disorders, low muscle tone and spasticity AHCY 1,2,19 Homozygous will lower homocysteine and glutathione CBS c699t Homozygous will lower homocysteine and glutathione SOD 1 Been found to affect the cytoplasm and mitochondria NOS 1 Decreased ability to metabolize nitric oxide NAT2 Homozygous can cause chemical avoidance VDR Homozygous results in decreased activity in receptor that transports Vitamin FOLR1 Primary folate receptor for cells