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CCK stimulation of GLP-1 neurons involves 1-adrenoceptor-mediated increase in glutamatergic synaptic inputs
For instance, as an increase in drug lipophilicity resulted in a proportionally higher BBB permeation rate, many drug delivery strategies were focused on an increase in lipophilicity of the CNS drugs (25)
Hogenkamp PS, Nilsson E, Nilsson VC, Chapman CD, Vogel H, Lundberg LS et al
Precision medicine approaches should enroll participants based on biological signatures rather than broad diagnostic categories, including glutathione status, lactate to pyruvate ratios, N acetyl aspartate, NRF2 related profiles, electron transport chain complex activity, and the presence of folate receptor alpha autoantibodies in cerebral folate deficiency
