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However, it is currently inconclusive what specific roles ferroptosis exerts during the development of the skin and appendages, as well as in the pathophysiological processes of cutaneous diseases

Once inside the mitochondrial matrix, a second enzyme, Carnitine Palmitoyltransferase 2 (CPT2), detaches the L-Carnitine, releasing the fatty acid so it can undergo beta-oxidationa process that breaks down the fat into acetyl-CoA

63 Nianiou-ObeidatI.MadesisP.KissoudisC.VoulgariG.ChronopoulouE.TsaftarisA.et al (2017)

Sitagliptin preserved the cell survival rate and against cellular apoptosis in situ ation of oxidative stress

Endocrinology 157 , 39723982 (2016)

A., & Garg, U