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They are not looking for another gamble
For weight management, NICE has approved liraglutide 3 mg (Saxenda) and semaglutide 2.4 mg (Wegovy) under specific criteria, including BMI thresholds and provision through specialist weight management services
Side effects are consistent with other GLP-1 medications and include nausea, vomiting, diarrhea, constipation, and stomach discomfort
In early 2026, Roche paid $100 million to secure a non-exclusive patent licence from Structures subsidiary Gasherbrum Bio, covering intellectual property relevant to CT-996, the oral GLP-1 compound Roche acquired through its $2.7 billion buyout of Carmot Therapeutics in late 2023
Clinical trials suggest it can lead to a weight reduction of 15-20% over a year, offering potentially better results than Ozempic
If you have type 2 diabetes and are at high risk for cardiovascular events, Semaglutide can help reduce this risk, offering an added layer of protection for your heart health
