Cycling off BPC157 after 46 weeks is recommended to mitigate unknown risks
Women of childbearing potential should note that Mounjaro is not recommended during pregnancy or breastfeeding, and additional contraceptive methods are advised for 4 weeks after starting treatment and after each dose increase
Patient safety is paramount when considering any medicine, and this is especially true for investigational drugs that have not yet completed the full regulatory approval process
These are harder endpoints to achieve but more clinically meaningful
Zhu Y, Sun J, Zhu Y, Wang L, and Qi B
Some good news: There was a concern that SGLT2 inhibitors would also increase the risk of urinary tract infection (one symptom of UTI is a persistent urge to urinate, per the Mayo Clinic), but research has failed to find that connection