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Double-edged roles of ferroptosis in endometriosis Endometriosis is also an oestrogen-dependent gynaecological disease in which excessive oestrogen signalling transduction and altered oestrogen signalling pathways play an important role in its pathogenesis, resulting in oestrogen dominance and progesterone resistance [97, 98]
The drug reaches systemic circulation independently of food intake, and its receptor-binding activity remains intact regardless of what a person eats
Note that this is considered off label and risks reduced efficacy, fluctuating appetite control, weight regain, glycaemic deterioration and dosing errors
& Heine, W
The KLOW vs KPV which better comparison at the mechanistic level comes down to target tissue
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