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Weight Loss in 6 Weeks on a GLP-1 Medication Trisha Paytas is not crying on her kitchen floor over this

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According to the retatrutide trial results, the share of people who quit due to side effects was similar to that in other GLP-1 trials (between 4% and 11%, depending on the dose)

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Its associated with alterations in your neuroendocrine appetite control mechanisms, specifically reduced leptin levels and an increase in ghrelin levels, both of which contribute to satiety and hunger, respectively