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AGA clinical practice update: diagnosis and management of nonalcoholic fatty liver disease in lean individuals: expert review

Unfortunately, these drugs may have negative effects on birth control and on pregnancies

However, the clinical evidence base for this specific combination in non-research contexts remains limited and heterogeneous

Additionally, while clinical guidelines for indicated use of GLP-1 RAs are rapidly changing as evidence for GLP-1 RA use evolves, the ethics of off-label use are particularly important to consider given the impact these shortages can have on access for patients who otherwise have a strong clinical indication to be on them

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