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Rosenstock J, Wysham C, Frias JP, Kaneko S, Lee CJ, Lando LF, et al

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Truist Securities analyst Joon Lee wrote in a note to investors that while efficacy looks strong relative to peers, we think CT-996 came up short on safety and tolerability. BMO Capital Markets analyst Evan Seigerman also acknowledged that CT-996s safety data leaves questions for some investors, who will likely choose to stay on the sidelines as they wait to see if the company can improve tolerability in Phase II studies

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Instead, the company developed a new ingredient, known generically as orforglipron, that's not a peptide like the injectable drugs, but acts like one

119 Detailly, breast cancer cells mimic the anti-inflammatory mechanism of central nervous system to evade antitumor immunity, which is dependent on the immunological synapse