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Despite these findings, Tesamorelin did not significantly affect liver enzymes such as alanine aminotransferase (ALT) and gamma-glutamyl transferase (GGT) overall

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Comparing efficacy on the basis of preclinical 5-Amino-1MQ data would be misleading

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The most dramatic result (mice returning to a body composition indistinguishable from lean age-matched animals) came from combining the inhibitor with a low-fat diet switch, and that study did not include a drug-alone arm

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