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doi: 10.3389/fanim.2025.1669519 Received 19 July 2025 Accepted 04 September 2025 Published 18 September 2025 Volume 6 - 2025 Edited by Muhammet Rasit Ugur, IVF Michigan Fertility Centers, United States Reviewed by Tlou Christopher Kujoana, University of South Africa, South Africa

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SAMe and methionine require context Methionine or SAMe may be useful in selected undermethylated patients but may be inappropriate with elevated homocysteine, high SAH or an uncertain methylation pattern

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Delivery of miR-26a using an exosomes-based nanosystem inhibited proliferation of hepatocellular carcinoma