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The SPR sensorgrams showed that 15 of the 18 amino acid substitutions accelerated dissociation from the receptor, and thus weakened the binding to FcRn (Fig

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Although this observation appears inconsistent with leptins inhibitory effect on insulin secretion, it can be explained by the restoration of leptin sensitivity after surgery

Vitamin D prevents hypoxia/reoxygenation-induced blood-brain barrier disruption via vitamin D receptor-mediated NF-kB signaling pathways