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4 Not only are GLP-1 and similar drugs highly effective at their original purpose of controlling blood sugar for diabetes, they are also much more effective than any previous weight loss medications

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No animals met these criteria, and thus none were excluded

GLP-1 Success Story GLP-1 agonists (also called GLP-1RAs), and related drugs like dual agonists of gastric inhibitory polypeptide (GIP)/GLP-1, have revolutionized obesity treatment by demonstrating significant and sustained weight loss in clinical trials and real-world use

Identification of determinants of glucose-dependent insulinotropic polypeptide receptor that interact with N-terminal biologically active region of the natural ligand