A seminal cost analysis published in Canadian Family Physician (2001) projected that switching patients from intramuscular B12 injections to oral supplements could save between $2.9 million and $17.6 million depending on the population studied with one Ontario analysis estimating $14.5 million in savings for 110,000 elderly patients
Study has shown that it has a very good tolerability and safety, thus the immune system does not form any antibodies against the AOD-9604 peptide
This regulatory limbo creates a side-effect risk that has nothing to do with the molecules themselves: product quality variation
Some have sited peptides stored at 39F have experienced minimal degradation
Taking B12 too close to bedtime can be stimulating for some people and may make it harder to fall asleep or stay asleep. If you notice any change in your sleep after starting B12, simply move your dose earlier in the day and track how you feel
Many patients start to feel better within a few days to a week after starting methylcobalamin injections, especially if they were significantly deficient