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They act as mighty messengers, sending signals to cells and tissues to perform a full spectrum of essential biological functions

This variance reflects genuine uncertainty in the literature combined with significant individual variation in response

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Cytokine modulation Beyond its effects on Tregs, thymosin alpha-1 directly reduces the production of IL-1beta and TNF-alpha, two cytokines central to psoriasis pathology

For states of systemic inflammation that involve cells of the peripheral immune system, while for neurodegenerative and neuroinflammatory diseases such as AD, PD, and MS, penetration of the CNS is necessary (Lin et al., 2024