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The former enables insertion into the mitochondrial membrane via lipophilic affinity, while the latter capacitate translocation into the mitochondrial matrix depending on the negative membrane potential, which can reach up to -180 mV

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Monothiol mechanism (i) and (iii) remain to be analyzed in more detail for HEDS and small non-glutathione disulfides

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Supplementation with extract of Gynostemma pentaphyllum leaves reduces anxiety in healthy subjects with chronic psychological stress: A randomized, double-blind, placebo-controlled clinical trial