-Glutamylcysteine ligase (GCL) is the rate limiting enzyme involved in GSH synthesis and its expression has been shown to be induced in response to CS [13]
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Huang et al., 2015), much like it is effective also in counteracting bleeding disorders (Stupnisek et al., 2012
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This helps maintain physiologic hormone patterns rather than overwhelming the body with synthetic GH
No statistically significant preoperative differences between groups were observed, with the exception of IL-8, which peaked at 6 hours after surgery in both groups but was significantly higher in the restriction group ( p = 0.018)