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Educational background: Tirzepatide as a molecule was developed by Eli Lilly and Company and is sold under the brand names Mounjaro (for type 2 diabetes) and Zepbound (for chronic weight management)

Patients with lower GLP1R sensitivity may benefit from tirzepatide (which targets dual pathways) instead of semaglutide alone

Tirzepatide (Zepbound for weight management

Saxagliptin is generally well tolerated and offers advantages including a low risk of hypoglycemia, weight neutrality, and convenient once-daily administration

Futile cycling of glucose has also been suggested to confer glucagons energy expenditure effects, whereby glucagon stimulates opposing pathways of hepatic glucose production and consumption (56)

How much water should I drink on GLP-1 medications