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Methods We adhered to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) extension for scoping reviews statement

[34] [35] In the brain, they act on satiety centers to reduce appetite and food intake

Swim latency, swim distance, time spent in the target quadrant, and number of quadrant crossings were recorded using a computerized video tracking system [1]

6.2 Challenges faced The half-life of natural PYY is extremely short (only about 812 minutes) (170) and requires frequent drug use, which seriously limits its clinical feasibility

the isocitrate dehydrogenase (IDH), which converts isocitrate to -ketoglutarate

Semaglutide may fit when additional A1C reduction, appetite effects, or weight-related health goals are important