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By improving HRV, L-carnitine helps shift the autonomic nervous system out of chronic sympathetic overdrive (the "fight or flight" state) and enhances parasympathetic vagal tone (the "rest and digest" state), promoting a calmer, more regulated nervous system response to physical stressors

as such, treatment has centered around their modification

S-Acetyl Glutathione (SAG) S-acetyl glutathione is a derivative in which an acetyl group is attached to the sulfur atom of the cysteine residue, theoretically protecting it from oxidation and enzymatic degradation in the gut

*Correspondence: Jana Frahm, [email protected] This article was submitted to Nutritional Immunology, a section of the journal Frontiers in Immunology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

However, it is available as a research chemical from various sources, with personal use falling into an ambiguous legal category

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