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@chiarthritis Replying to @debbiereid4607 Asked and answered

The largest trial of ERAs, SONAR, including 2648 participants with type 2 diabetes and proteinuric CKD, demonstrated that atrasentan on top of RAS inhibition significantly lowered the risk of a doubling of serum creatinine or ESKD compared with placebo by 35% [75]

These receptors are part of a system that controls different body functions

Therapeutic Advances in Endocrinology and Metabolism, 12