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Die erste Studie mit einem klaren Nutzen war EMPA-REG OUTCOME: Empagliflozin reduzierte das Risiko fr 3-Punkte-MACE um 14 %, die kardiovaskulre Mortalitt um 38 %, Hospitalisationen wegen Herzinsuffizienz um 35 % und die Gesamtmortalitt um 32 %