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ABHD5 stimulates PNPLA1-mediated O -acylceramide biosynthesis essential for a functional skin permeability barrier

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Limit processed low-fiber foods (white bread, pasta), cheese and dairy, red meat, unripe bananas, and fried foods

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Baseline laboratory evaluation should include a complete blood count with differential, comprehensive metabolic panel, hepatic function tests, and tumor markers selected according to the patients demographics, family history, and clinical context

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