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J Clin Invest 1996

At the 12mg maintenance dose, approximately 21% of participants reported constipation

[263] [265] The book's preface is by Mark Hyman, a proponent of the alternative medical treatment called functional medicine

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In hemodialysis patients, due to reduced renal clearance, carnitine depletion and acylcarnitine accumulation become significant, resulting in an abnormal increase in the ratio of acylcarnitine to free carnitine in plasma, which in turn inhibits cardiac fatty acid metabolism [261]