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Rheumatoid arthritis, an autoimmune condition, causes inflammation and structural changes in the spine, which may contribute to canal narrowing and an increased likelihood of nerve compression

Since training and competition create more oxidative stress and damage, athletes have a higher need for antioxidants

Their organization into broad categories represents an interconnected hierarchy where the primary hallmarks reflect macromolecular damage (i.e., genome, proteome, organelles) which lead to antagonistic hallmarks, e.g., response to the damage

2021 Dec 27;11(1):50

Hess DT, Matsumoto A, Kim SO, Marshall HE, Stamler JS